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Selective haematological cancer eradication with preserved haematopoiesis

by admin | May 22, 2024 | Publication

Selective haematological cancer eradication with preserved haematopoiesis Simon Garaudé1,2,15,Romina Marone1,2,15, Rosalba Lepore1,2,3, Anna Devaux1,2, Astrid Beerlage1,2,4, Denis Seyres1,2, Alessandro Dell’ Aglio1,2, Darius Juskevicius5, Jessica Zuin1,2, Thomas...

Molecular shielding of CD52 retains expression, anti-phagocytic ‘don’t eat me’ function and protects from Alemtuzumab-mediated depletion

by admin | May 13, 2024 | Publication

Molecular shielding of CD52 retains expression, anti-phagocytic ‘don’t eat me’ function and protects from Alemtuzumab-mediated depletion Anna Camus1*, Emiel ten Buren1*, Laura Garcia-Prat1, Julie Brault1, Valentin Do Sacramento1, Sophie Lackner1, Rosalba Lepore1,2,...

Base-Edited HSPCs Are Shielded from Targeted CD33 Therapy but Preserve CD33 Expression

by admin | Dec 16, 2023 | Publication

Base-Edited HSPCs Are Shielded from Targeted CD33 Therapy but Preserve CD33 Expression Astrid Beerlage, MD1,2, Simon Garaudé1,2, Rosalba Lepore, PhD1,2,3, Thomas Burgold, PhD1,2,3, Anna Camus, PhD3, Mathilde Testut3, Stefanie Urlinger, PhD3 and Lukas T Jeker, MD...

Hematopoietic Stem Cells Expressing Engineered CD45 Enable a Near Universal Targeted Therapy for Hematologic Diseases

by admin | Dec 16, 2023 | Publication

Hematopoietic Stem Cells Expressing Engineered CD45 Enable a Near Universal Targeted Therapy for Hematologic Diseases Romina Marone1,2*, Simon Garaudé1,2*, Rosalba Lepore1, 2, 3, Anna Devaux1,2, Astrid Beerlage1, 2, Federico Simonetta4,5, Anna Camus3, Izabela...

Epitope-engineered human hematopoietic stem cells are shielded from CD123-targeted immunotherapy

by admin | Sep 29, 2023 | Publication

Epitope-engineered human hematopoietic stem cells are shielded from CD123-targeted immunotherapy Romina Marone1,2, Emmanuelle Landmann1,2, Anna Devaux1,2, Rosalba Lepore1,2,3,4, Denis Seyres1,2, Jessica Zuin1,2, Thomas Burgold1,2, Corinne Engdahl1,2, Giuseppina...

Molecular Shielding of the Pan-Hematopoietic Marker CD45 May Enable a Targeted Universal Approach for Replacement of the Hematopoietic System

by admin | May 31, 2023 | Publication

Molecular Shielding of the Pan-Hematopoietic Marker CD45 May Enable a Targeted Universal Approach for Replacement of the Hematopoietic System Simon Garaudé1, Romina Marone1, Rosalba Lepore1,2, Anna Devaux1, Anna Camus2, Izabela Durzynska2,3, Eva-Maria Grossjohann2,...
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Recent Posts

  • Cimeio Therapeutics Announces Partnership with Kyowa Kirin to Develop Novel Cell Therapies
  • Cimeio Therapeutics Therapy Platform Featured in Forbes Article
  • Selective haematological cancer eradication with preserved haematopoiesis
  • Cimeio Therapeutics Announces Publication in Nature Demonstrating That CD45 ADC and Shielded HSCs Represent a Potentially Universal Therapy for Blood Cancers
  • Molecular shielding of CD52 retains expression, anti-phagocytic ‘don’t eat me’ function and protects from Alemtuzumab-mediated depletion

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